SkinGun™ and CellMist™ Technology Overview

RenovaCare is developing breakthrough technologies to address America’s $45 billion wound and burn treatment market. Our flagship CellMist™ System makes use of a patient’s own stem cells, which are sprayed onto wounds using our novel SkinGun™ device.

For patients suffering severe burns and other wounds, the prospect of a quick-healing, gentle spray containing their own stem cells will be a promising alternative to conventional skin graft surgery, which can be painful, prone to complications, and slow-to-heal.

Based on preliminary case studies, CellMist™ System patients can be treated within 90 minutes of arriving in an emergency room; a patient’s stem cells are isolated, processed, and sprayed on to wound sites for rapid healing.

RenovaCare products are under development and not approved for sale in the United States.

Preliminary investigational use in Europe and the United States indicate the potential efficacy and safety of RenovaCare’s technologies. Clinical observations point to the potential for regeneration of new skin in as little as four days, rather than the many weeks of painful and risky recovery required by traditional skin graft techniques.

These technologies are the result of nearly a decade of ongoing research and development dedicated to finding the most effective way to access the regenerative properties of a patient’s own skin stem cells, and the most efficient way to deliver these potent cells to heal moderate to severe skin wounds.

We believe that RenovaCare’s CellMist™ System and SkinGun™ spray device are the world’s most advanced technologies of their kind.

This device system requires further clinical evaluation and data collection prior to submission of a premarketing application to the US FDA. At this time it is an investigational system and is not available for general use or sales in the United States.

The CellMist™ System

RenovaCare’s CellMist™ System is comprised of two components:

  1. CellMist™ Solution
    A liquid suspension of the patient’s own stem cells
  2. SkinGun™
    An ultra-gentle spray device which delicately deposits the CellMist™ Solution on to a patient’s wounds

What is the CellMist™ Solution?

The CellMist™ Solution is a liquid suspension containing a patient’s own regenerative skin stem cells. A small sample (as little as a square inch) of the patient’s skin is quickly processed to liberate the stem cells from surrounding tissue. The resulting product is referred to as the ‘CellMist™ Solution’. The CellMist™ Solution is placed in the SkinGun™ for spray application onto the patient’s wound.

What is the SkinGun™?

The CellMist™ Solution, containing the patient’s stem cells, is transferred to the SkinGun™. The SkinGun™ sprays the cells onto wound sites to begin healing. Unlike conventional aerosol and pump systems, our next-generation fluid sprayer does not expose fragile cells to strong forces that can tear them apart. Instead our SkinGun™ gently delivers the CellMist™ Solution directly to the wound site using a positive-pressure air stream.